The software giant has reduced the number of Office versions to three, compared to the five that were available for Office 2007, in a bid to "simplify" the purchasing process.
A boxed copy of Office 2010 Home and Student, which includes Word, Excel, PowerPoint and OneNote and can be installed on up to three computers, will cost £109.99. A copy of Office 2010 Home and Business that also includes Outlook and can be used on two PCs costs £239.99.
Alternatively, Office 2010 Professional offers all of these programs along with Publisher and Microsoft's desktop database software, Access, for £429.99 for a two-PC licence.
Microsoft said each version of Office 2010 will also be available as a 'product key card' (PKC), that will allow users buying Office 2010 with a new PC.
The PKC, which costs slightly less than a boxed copy, will allow users to unlock the relevant Office 2010 software that has been pre-loaded by PC manufacturers on the machine.
A 'product key card' for Office 2010 Home Business is £89.99, while they are priced at £189.99 and £299.99 for Office 2010 Home and Business and Office 2010 Professional, respectively.
Microsoft also said it is replacing Microsoft Works, the trimmed down edition of the office suite that comes pre-installed on some new PCs, with Office Starter 2010.
All versions of Office 2010 also come with Office Web Apps, the bare-bones online Word, Excel, PowerPoint and OneNote applications that consumers can use for free via Windows Liv.
The full version of Office 2010, which is currently available in beta, will be released in June.