Most of these ad and pop-up blockers are freebies or have free trials, so give one a go. If its performance isn't up to your standards, uninstall it and try others until you find one that's a perfect fit with the way you browse.
Get rid of pesky pop-ups, the easy way
Browser add-ons and extensions, part II
Quero Toolbar 4.0
Quero Toolbar 4.0 is a free toolbar for Internet Explorer that blocks pop-ups, banners, Flash ads, framed ads, layered ads, and even Google text ads; it's also a great search helper with access to 18 search tools.
In addition, Quero has an array of other useful features, including a means to change IE's windows into prearranged sizes, modify the size of the text on a page, and guard against phishing expeditions.
One nice touch is that you can add plenty of other search-engine choices to the 18 engines that Quero already has in its search box. What's more, you can separate the collection of search engines into categories, such as "shopping" or "help sites".
Another cool feature: you can use Quero to bring the more familiar look of Internet Explorer 6.0 to the IE7 interface. For instance, after installing the toolbar, choose Hide standard address/navigation bar under the Appearance option, and then move the menu bar back up top. Quero Toolbar 4.0 works with any version of Windows, but only with Internet Explorer (5.0 and newer).
Download Quero Toolbar 4.0
sQusi is an IE add-on and Firefox extension freebie that blocks ads, stops Flash and pop-ups, and nails Google's inline IntelliTXT. The program also automatically blocks cookies, stops embedded music players, and halts advertisers' web beacons. It blocks ads embedded in Windows Messenger Live and Yahoo IM applications, too. The program lets you blacklist or whitelist entire sites and clean both Firefox and Internet Explorer cache folders, as well as remove cookies.
Download sQusi 2.0