The UK Defence Secretary, Liam Fox, is calling for game retailers to boycott the next version of Medal of Honor to "show their support for the armed forces".
The game, which is expected to hit UK shelves in October, will give players the chance to fight on the side of the Taliban.
"At the hands of the Taliban, children have lost fathers and wives have lost husbands. It's shocking that someone would think it acceptable to recreate the acts of the Taliban against British soldiers," Fox said in a statement.
"I am disgusted and angry. It's hard to believe any citizen of our country would wish to buy such a thoroughly un-British game. I would urge retailers to show their support for our armed forces and ban this tasteless product."
However, Electronic Arts, which created the game series, said the new title will give gamers "the opportunity to play both sides" and that no British troops are featured.
"Nobody who plays video games is going to be shocked or surprised by this. Most of us have been doing this since we were seven: someone plays the cop, someone must be robber."
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