The usual as with any laptops. Check to see what software is available for trial. Do not open them. Decide what you don't need and uninstall through programs and features. Usually security software trials.
Win 8 comes with Defender and its own firewall so it is protected from new.
Once you find your way around, find how to create your factory restore discs and create them as soon as you can. There is no key label on Win 8 laptops.
Create a user that has a Microsoft email, ie hotmail, live mail or the new Outlook and use the email password to log in. This allows the use of all the tiles. That means the email address is the user name.
Later I would create a second Standard admin account, call it Stand-by, or similar, in case you run into difficulty with the original profile. This is just a backup account.