The floating menu moves when you move the mouse, most of the screen area is wasted with the relevant text in a small box in the middle. I don't know if the Donate popup is part of the design, but I cannot imagine anything more irritating.
Sorry not to have anything good to say, but I wouldn't even be tempted to go past the first screen. Design for 800 x 600 and use all the space. I tried in Internet Explorer too, just in case it was a problem with Opera, but at least in Opera one can zoom in to be able to read the text.