The settings you listed are really just 'tweak' settings and should be set fairly well at default. If all of your games were running badly I would guess that one of these settings was wrong. But, as its just this one game I doubt altering these settings would do anything.
Have you downloaded the latest drivers for your graphics card?
Take a look at the video settings in the game :-
Turn the resolution to minimum settings and see what happens.
Take a look at the video mode you are running in, is it openGL?
Basically turn ALL the video/graphics settings to their minumim and see if the game is still slow and jerky.