Shouldn't be any difference.
I connect my MS Media Keyboard and Logitech MX518 mouse using PS/2. I prefer not to waste a couple of USB ports on my keyboard/mouse when the PS/2 sockets work just as well.
Huawei P10 review
1995-2015: How technology has changed the world in 20 years
An overview: What leading creative agencies are doing to improve diversity
New iPad, iPhone SE & Red iPhone 7 on sale now
Synology invites you to visit them at Insomnia on 26th – 29th August. Book your tickets now and visit Synology.