You can, and I do. However, you will still have problems when you re-install your operating system. Some of your programs will still work. BUT!!! Most of the programs install themselves with information going into Registry, which, of course, you lose as soon as you start to re-install, and all these will have to be reinstalled. However, you will have the advantage that you are re-installing over the top and you could find that many of your settings will be safe.