ok so here it is when i move my mouse up the cursor moves to the left down= right and so as if it has been rotated 90 degrees anti-clockwise i have seen topic about this as wellbut none seem to work i am using a wireless mouse could there be a way to realign/calibrate the mouse
There is no way to "calibrate" a mouse. When you used Device Manager did you choose "Browse my computer for driver software" ?
Alternatively search for driver for your particular mouse. If you type "mouse drivers" and then the type of computer you have and the OS into google, or better yet the type of mouse as well, you'll probably find the drivers to download.