Defragging difficulty

  m800afc 09:02 19 Aug 08

Win XP pro, sp3
Yesterday I defragged my laptop. On comletion the defrag report indicated that large portions of the disk, approx 14Gb could not be defragged. I ran chkdsk and nothing was reported. I ran the analysys part of O&O Defrag, and the graphio showed a large portion of the drive to be "Locked". I then ran chkssk /f, and this ran without problems.
How can I "Unlock" these areas of the drive, and defrag my drive thoroughly?

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