Hi darkjedimistress. The first consideration when scanning the pictures is what you want the pictures to be used for. The number of colours doesn't have much effect on the file size, but the number of pixels does. If you have graphics processing that gives you control of the jpeg compression factor, this will enable you to get smaller files even with a relatively large number of pixels, but even basic software such as Irfanview enables you to resample to a smaller number of pixels. If the scanned photo is to be viewed on a computer monitor, match the resolution to the monitor, i.e. if the monitor resolution is 1024 x 768 pixels, then there is no point in going higher than this, and 1024 pixels from a 6 inch photo is only 170pixels per inch. If the photo is to be printed at 6 inches x 4 inches, then the same resolution will also be enough, and equates to nearly 1Mp from a digital camera.