I have this running om my XP box.
It seems to have worked once.
"11/03/2007 14:20:08: TROJ-AGENT.OE VARIANT STOPPED BY BOCLEAN!
Trojan horse was found in memory.
P:\LAUNCHER.EXE contained the trojan.
Active trojan horse WAS shut down. System safe.
Logged in user: Steve"
It runs in the background with just a tray icon.
Don't know how much you need it but it can give a bit more peace of mind.