The text below might be of help to you.
A: Drive accessed when opening My Computer, etc?
Lifted from PC Answers Issue 106 (May 2002), Pg.81.
Alter the following registry key as shown below.
95 00 00 00 (Was 99 00 00 00 or 91 00 00 00 as set by X-Setup for Auto Start on removable media, Zip drives, etc.)
A problem with the above solution is that it also stops other removable media e.g. Castlewood Orb drive, from auto running. A more drive specific solution is to add the NoDriveAutoRun DWORD under the same key. When the DWORD is added the default value is 0x00000000 (0). Each drive is given a value starting with A through to Z. A = 1, B=2, C=3, D=4, etc. To stop the autorun for the A Drive set the DWORD value to 0x00000001 (1).
The value for each drive is 0 for “on” and 1 for “off” using a binary value with the least significant digit for drive A, the next significant digit for drive B, the next significant digit for drive C, etc.
e.g. 101 to disable autorun for drives A & C, 110 to disable autorun for drives B & C, 1001 to disable autorun for drives A & D. This value needs to be translated from binary to hexadecimal before it is used as the DWORD value. Thus 101 becomes 5 and is used as the DWORD value of 0x00000005 (5) to disable autorun on drives A & C.