The twain folder appears in the Windows root directory as a'TWUNK' file/folder I believe- have a look and consider deleting one if you can I/D it.
However dont rush wait until a Windoze expert comes in.
Surface Pro (2017) vs Surface Pro 4
20 groundbreaking 3D animation technologies coming to Siggraph 2017
iPad Pro 12.9 vs Surface Pro 5
Synology invites you to visit them at Insomnia on 26th – 29th August. Book your tickets now and visit Synology.