The "best Registry Cleaner" would depend on how advanced you are with these products, because some can and do cause more harm than good, in the wrong hands.
One of the 'safest and easy to use', would in my view be CCleaner.
Hands-on: Acer Predator Triton 700 review
D&AD Awards 2017: see the best design, advertising, illustration, animation and VR of the past year
How to lose weight with an Apple Watch
Synology invites you to visit them at Insomnia on 26th – 29th August. Book your tickets now and visit Synology.